Reported Characteristics
Drug Class: Narcotic/Analgesic (For injection)
Average Reported Dosage: 2.5-10.0 MG (0.25-1.0 ML) every 3 hours.

The first thing the reader should consider when reading this drug profile is “what is a narcotic drug doing in a book about bodybuilding chemistry? ” And in no way, assume any good did or could come from its use. Nubain is an injectable pain-killer similar to morphine in action and effect. In fact, the activity is about the same, as is its addictive potential, milligram for milligram. This is because Nubain is a synthetic opiate agonist/antagonist. The only positive aspect of Nubain is the fact that the drug is self-leveling (agonist/antagonist) which mostly prevents potential over-dosing. Dan Duchaine (the original steroid guru) has been credited with introducing Nubain to the athletic world, though its use in sports pre-dates Dan’s commentary. Dan speculated that Nubain maybe a viable anti-cortisol/anticatabolic drug with Lipolytic (fat burning) qualities. Dan was a genius when it came to thinking outside the box. But he missed on this one. (And should not be totally blamed by those addicted to it) Bodybuilders used Nubain (the crazy ones) as an intended thermogenic, anti-catabolic, and as a means of suppressing the pain of injuries from years of balls-out training.

This may have some validity since the drug does reduce an individual’s perception of stress, and is a powerful appetite suppressant. And like any opiate, the drug allowed some reported users to train well beyond the pain barrier threshold resulting in greater muscle fiber stimulation. So a lower perception of stress would slightly reduce total cortisol production. And an appetite fall-off would reduce total calorie intake while increased training intensity would increase calorie expenditure. But the fact is that the drug is no more thermogenic or anti-catabolic than any narcotic…just far more addictive. Some have speculated that Nubain will be replaced by heroin. Don’t laugh, Nubain is scheduled for manufacturer’s discontinuance. If the reader has seen Nubain users during withdrawal, the facts speak unwell for the future.

Dan Duchaine was a very resourceful individual and, though an ass at times, supplied an answer to an urgent request for help to those he cared for. In this case, a client who suffered two prior attempts at kicking Nubain, and was ready for another try out of necessity. Dan’s answer was a drug called Ultram, which is in the same drug class as Nubain but more like the clinical answer to heroin is Methadone. The client had a bit of an attitude but suffered no diarrhea no anxiety, no fever, or coughing, or sneezing. And he stated little or no Nubain craving resulted. He is Ultram/Nubain free still.

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